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L-Glutamine

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L-Glutamine contains 850 mg of l-glutamine per serving (one capsule). This amino acid is essential for the health of the immune system and the GI tract. In the gut, it is a fuel source for the enterocytes (cells of the intestinal lining)

BENEFITS

  • Supports healthy digestion
  • Supports muscle growth and aids in muscle repair
  • Promotes a healthy immune response
  • Fuel source for cells in the gut (enterocytes)
  • Fuel source for lymphocytes (type of white blood cell)
  • Helps to form secretory IgA (SIgA), which is your first line of defense
  • Needed to help heal the lining of the gut
  • Helps produce glutathione
  • Helps produce nitric oxide to help blood vessels dilate

Dosage
Take 1 cap per day or as directed by your health care professional.

Description

NutriRestore offers L-Glutamine, a free-form amino acid, in two delivery options: vegetarian capsules
(850 mg of glutamine per capsule) and a powdered form (3 grams per 3/4 teaspoon serving). Glutamine is the body’s most abundant free-form amino acid, representing approximately 40% to 60% of the total amino acid pool in the body. Glutamine is required to perform a variety of essential functions.

Often referred to as the multitasker, glutamine is a nutrient with an impressive range of health benefits. It helps support normal blood glucose metabolism, build lean muscle, and promote a normal immune response. In the gut, glutamine promotes the health and function of the mucosal cells for normal repair. Furthermore, glutamine distributes nitrogen freely to the cells that need it the most, such as the immune cells, the gut cells, and the muscle cells. Glutamine is also fuel for brain cells, which helps to maintain mental energy.

Glutamine Support

  • Gut integrity: By fueling the mucosal cells of the intestine, glutamine helps strengthens the integrity of the intestinal wall to support a healthy gastrointestinal tract
  • Immune Support: Provides a major source of energy for the immune system and its varied cells. Glutamine is an excellent nutrient for immune support
  • Maintenance of Muscle Tissue: Supports muscle recovery during sporting events or exercise and play a role in the prevention of reduce soreness
  • Antioxidant: Increases production of glutathione, the body’s main antioxidant, and supports a healthy immune response by protecting tissues from oxidative damage and helping to support the body’s natural detoxification of harmful substances
  • Brain Support: An important precursor to the production of neurotransmitter substances in the brain and helps to support wellness of the brain and mental energy

References

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

 

  1. Cruzat, V., Macedo Rogero, M., Noel Keane, K., Curi, R., & Newsholme, P. (2018). Glutamine: Metabolism and immune function, supplementation and clinical translation. Nutrients, 10(11), 1564. DOI:10.3390/nu10111564
  2. Altman, B. J., Stine, Z. E., & Dang, C. V. (2016). From Krebs to clinic: glutamine metabolism to cancer therapy. Nature Reviews: Cancer, 16(10), 619–634. DOI:10.1038/nrc.2016.71
  3. Kim, B., Li, J., Jang, C., & Arany, Z. (2017). Glutamine fuels proliferation but not migration of endothelial cells. The EMBO Journal, 36(16), 2321–2333. DOI:10.15252/embj.201796436
  4. Faisal, S., Tarfarosh, A., Tromboo, U. & Bhat, F. (2017). Search for a perfect nootropic supplement combination – Can we increase human intelligence by nutritional supplements? Journal of Pharmacognosy and Phytochemistry, 6(5), 1020-1024. Retrieved from http://www.phytojournal.com/archives/2017/vol6issue5/PartO/6-5-56-427.pdf
  5. Caris, A. V., Da Silva, E. T., Dos Santos, S. A., Tufik, S., & Dos Santos, R. (2017). Effects of carbohydrate and glutamine supplementation on oral mucosa immunity after strenuous exercise at high altitude: A double-blind randomized trial. Nutrients, 9(7), 692. DOI:10.3390/nu9070692
  6. Legault, Z., Bagnall, N., & Kimmerly, D. S. (2015). The influence of oral L-glutamine supplementation on muscle strength recovery and soreness following unilateral knee extension eccentric exercise. International Journal of Sports Nutrition and Exercise Metabolism, 25(5), 417-426. DOI: 10.1123/ijsnem.2014-0209
  7. Kim, M. H., & Kim, H. (2017). The roles of glutamine in the intestine and its implication in intestinal diseases. International Journal of Molecular Sciences, 18(5), 1051. DOI:10.3390/ijms18051051
  8. Pugh, J. N., Sage, S., Hutson, M., Doran, D. A., Fleming, S. C., Highton, J., … Close, G. L. (2017). Glutamine supplementation reduces markers of intestinal permeability during running in the heat in a dose-dependent manner. European Journal of Applied Physiology, 117(12), 2569–2577. DOI:10.1007/s00421-017-3744-4
  9. De Souza, A. Z., Zambom, A. Z., Abboud, K. Y., Reis, S. K., Tannihao, F., Guadagnini, D., … Prada, P. O. (2015). Oral supplementation with L-glutamine alters gut microbiota of obese and overweight adults: A pilot study. Nutrition, 31(6), 884-889. DOI: 10.1016/j.nut.2015.01.004
  10. Wang, K., Hoshino, Y., Dowdell, K., Bosch-Marce, M., Myers, T. G., Sarmiento, M., … Cohen, J. I. (2017). Glutamine supplementation suppresses herpes simplex virus reactivation. The Journal of Clinical Investigation, 127(7), 2626–2630. DOI:10.1172/JCI88990
  11. Shu, X. L., Yu, T. T., Kang, K., & Zhao, J. (2016). Effects of glutamine on markers of intestinal inflammatory response and mucosal permeability in abdominal surgery patients: A meta-analysis. Experimental and Therapeutic Medicine, 12(6), 3499–3506. DOI:10.3892/etm.2016.3799
  12. Reena, V. T., Gopichandran, L., Sumit, S., & Muthuvenkatachalam, S. (2016). Comparison of glutamine enriched feed over normal routine feed in traumatic brain injury patients: A randomized double-blind controlled trial. Asain Journal of Nursing Education and Research, 6(4), 485-490. DOI: 10.5958/2349-2996.2016.00091.4
  13. Al Balushi, R. M., Paratz, J. D., Cohen, J., & Banks, M. (2016). Glutamine supplementation in multiple trauma of critical care. In: Rajendram, R., Preedy V.R., & Patel V.B. (Eds.), Diet and Nutrition in Critical Care (203-218). New York, NY: Springer. https://doi.org/10.1007/978-1-4614-7836-2_141
  14. Brami, C., Bao, T., & Deng, G. (2016). Natural products and complementary therapies for chemotherapy-induced peripheral neuropathy: A systematic review. Critical Reviews in Oncology/hematology, 98, 325–334. DOI:10.1016/j. critrevonc.2015.11.014
  15. Chang, Y. H., Yu, M.S., Wu, K. H., Hsu, M. C., Chiou, Y. H., Wu, H. P., … Chao, Y. H. (2017). Effectiveness of parenteral glutamine on methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia. Nutrition & Cancer, 69(5), 746-751. DOI: 10.1080/01635581.2017.1324995.

Warnings

Always be sure to speak with your healthcare provider before starting any new nutritional supplement when pregnant or nursing. For children, we recommend speaking with your child's pediatrician regarding proper dosing. Store away from children.

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