Methyl Folate

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Methyl Folate contains the natural, biologically active form of folate, which is essential for cell division and growth along with many other functions. This form of folate has been shown to help increase blood folate levels much better than folic acid.


  • Supports healthy fetal development
  • Helps maintain proper homocysteine levels by supporting methylation
  • Supports balanced moods and a positive mental outlook
  • Aids in the relief of occasional nervous tension
  • Helps maintain healthy cardiovascular function
  • Required for optimal detoxification
  • Plays a role in DNA and RNA synthesis
  • Helps form red blood cells
  • Needed to help cells grow

Take one capsule per day, or as directed by your health care professional.


Methyl Folate provides a bioidentical, bioactive form of folate – a member of the B vitamin family – called 5-methyltetrahydrofolate or L-5-MTHF. This is the active circulating form of folate found in the body and one of the several forms naturally occurring in food. It is a patented folate derivative with high solubility, bioavailability and long-lasting stability. Folate is an essential nutrient needed during rapid cell division and growth; therefore, it comes as no surprise that pregnancy doubles the need for dietary folates. Folate also plays an important role in helping to maintain proper homocysteine levels. It is important to support healthy levels of this compound, as an optimally functioning homocysteine pathway provides nutrients for necessary biochemical reactions in the body. Folate vs. Folic Acid While folates are naturally occurring in food, folic acid is a synthetic compound used in many dietary supplements and in food fortification, but is not found in nature. Before the body can use folic acid, it requires enzymes and other nutrients to convert folic acid into usable 5-MTHF. If this does not occur properly, folic acid may accumulate in the blood and this has been associated with adverse health effects. Since L-5-MTHF is already in the active form, conversion is unnecessary, which makes supplementing with this form a safer and more effective choice than synthetic folic acid for maintaining healthy blood folate levels. Folate Deficiency Even the best efforts to eat a healthy diet may not deter a folate deficiency. Natural folates are easily destroyed during cooking or processing food. Additionally, many over-the-counter medications and prescription medications may interfere with folate absorption. Genetics is another factor that may affect folate metabolism. Natural variants of certain genes responsible for creating enzymes involved in converting folic acid into folate are common, so it may be best for these individuals to consume folate in the natural L-5-MTHF form.


† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


  1. Ebara S. Nutritional role of folate. Congenit Anom. 2017 Sep;57(5):138-141
  2. Sobczynska-Malefora A, Harrington DJ. Laboratory assessment of folate (vitamin B9) status. J Clin Pathol. 2018 Nov;71(11):949-956.
  3. Crider KS, Yang TP, et al. Folate and DNA methylation: a review of molecular mechanisms and the evidence of folate’s role. Adv Nutr. 2012 Jan;3(1):21-38.
  4. Miller AL. The methylation, neurotransmitter, and antioxidant connections between folate and depression. Altern Med Rev. 2008 Sep;13(3): 216-26.


Always be sure to speak with your healthcare provider before starting any new nutritional supplement when pregnant or nursing. For children, we recommend speaking with your child's pediatrician regarding proper dosing. Store away from children.


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