Description
Ingredients
Purified Zeolite (G-PUR®)
Zeolite is a natural porous rock containing minerals known to adsorb mycological agents and heavy metals (such as lead and mercury) in the digestive tract. It ionically binds to heavy metals and entraps toxins, holding them securely for safe elimination. A purified form of zeolite known as clinoptilolite (G-PUR®) is not absorbed in the GI tract and is highly resistant to degradation from acidic environments, making it especially useful for the removal of various toxic compounds throughout the GI tract. In both human and animal studies, clinoptilolite has been shown to successfully bind to mycological agents, ethanol, dietary cholesterol and heavy metals (e.g., cadmium and lead), which subsequently inhibits the bioavailability of these substances and finally eliminates them via stool. Additionally, approximately 300 mg of zeolite-clinoptilolite for 12 weeks has been shown to strengthen the integrity of the gut lining and maintain normal inflammatory balance. G-PUR® clinoptilolite is sourced from a mineral-rich quarry in Slovakia, where it is rigorously tested for inorganic impurities, evaluated for quality using highly specified standardization protocols, and purified for safety and efficacy. The microscopic structure of G-PUR® is shown to have cup-shaped clinoptilolite crystals, which acts as a magnet for heavy metals. In addition, G-PUR® has the highest purity of clinoptilolite, with homogeneity of fine matrix crystals without fibrous or needleshaped structures.
Activated Charcoal
Activated charcoal is a broad-spectrum binder that will bind most substances, including undesirable toxins but also beneficial vitamins and minerals. Activated charcoal has a long history of use as a binder in removing a variety of toxins from the body. During the manufacturing process, the charcoal is “activated” by creating holes within its structure. Activated charcoal contains a negatively charged, porous texture that helps attract toxins, preventing their absorption into the gut lining. Also, activated charcoal is composed of a carbon lattice structure that makes it ideal for trapping and removing toxins. Because activated charcoal is not absorbed by the body, it can safely carry the toxins bound to its surface out of the body.
Purified Shilajit (PrimaVie®)
Shilajit is an ancient Ayurvedic powder extracted from rocks high in the Himalayas, studied extensively through contemporary science for its safety and efficacy. It contains more than 40 different minerals, including fulvic acid and humic acid, which are shown to bind to a variety of toxins, improve endothelial function, and support a healthy microbiome.
Humic and fulvic acids are organic acids that have been studied in agriculture for their adsorbent properties, which allows them to bind and chelate various noxious agents such as environmental heavy metals pesticides and organic pollutants, and mycological agents. For example, a derivative of humic acid, oxihumate, was shown to bind to unwanted organisms and have a beneficial effect on body weight. Beneficial effects on gut ecology have also been reported in animals supplemented with humic acids, including increased intestinal villi height and crypt depth, stimulation of improved feed digestion, promotion of the formation of a protective layer on the mucus epithelia, and modulation of the gut microbiota.
PrimaVie® shilajit is highly purified, sourced from the mountains in central Asia. It is rich in diverse bioactive compounds including humic and fulvic acids, free and conjugated dibenzoalpha-pyrones (DBPs, also known as urolithins) and more than 40 minerals. These constituents give PrimaVie® shilajit diverse bioactivity (e.g., toxin binding, interaction with the gut microbiota, improved endothelial function, antioxidant effects, etc.)
References
- G-PUR. G-PUR/Purified Clinoptilolite Whitepaper. In. Synyrna, GA2017:45.
- Afriyie-Gyawu E, Ankrah NA, Huebner HJ, et al. NovaSil clay intervention in Ghanaians at high risk for aflatoxicosis. I. Study design and clinical outcomes. Food additives & contaminants Part A, Chemistry, analysis, control, exposure & risk assessment. 2008;25(1):76-87.
- Wang P, Afriyie-Gyawu E, Tang Y, et al. NovaSil clay intervention in Ghanaians at high risk for aflatoxicosis: II. Reduction in biomarkers of aflatoxin exposure in blood and urine. Food additives & contaminants Part A, Chemistry, analysis, control, exposure & risk assessment. 2008;25(5):622-634.
- Phillips TD, Afriyie-Gyawu E, Williams J, et al. Reducing human exposure to aflatoxin through the use of clay: a review. Food additives & contaminants Part A, Chemistry, analysis, control, exposure & risk assessment. 2008;25(2):134-145.
- Federico A, Dallio M, Gravina AG, et al. A pilot study on the ability of clinoptilolite to absorb ethanol in vivo in healthy drinkers: effect of gender. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2015;66(3):441- 447.
- Beltcheva M, Metcheva R, Popov N, et al. Modified natural clinoptilolite detoxifies small mammal’s organism loaded with lead I. Lead disposition and kinetic model for lead bioaccumulation. Biological trace element research. 2012;147(1- 3):180-188.
- Lamprecht M, Bogner S, Steinbauer K, et al. Effects of zeolite supplementation on parameters of intestinal barrier integrity, inflammation, redoxbiology and performance in aerobically trained subjects. J Int Soc Sports Nutr. 2015;12(1):40.
- Gratuito MK, Panyathanmaporn T, Chumnanklang RA, Sirinuntawittaya N, Dutta A. Production of activated carbon from coconut shell: optimization using response surface methodology. Bioresource technology. 2008;99(11):4887-4895.
- Zellner T, Prasa D, Färber E, Hoffmann-Walbeck P, Genser D, Eyer F. The Use of Activated Charcoal to Treat Intoxications. Dtsch Arztebl Int. 2019;116(18):311-317.
- Niranjan K, Ramakanth GSH, Nishat F, Usharani P. Evaluation of the Effect of Purified Aqueous Extract of Shilajit in Modifying Cardiovacular Risk with Special Reference to Endothelial Dysfunction in Patients with Type 2 Diabetes Mellitus. International Journal of Ayurveda and Pharma Research. 2016;4(4).
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- Zhang Z, Shi W, Ma H, et al. Binding Mechanism Between Fulvic Acid and Heavy Metals: Integrated Interpretation of Binding Experiments, Fraction Characterizations, and Models. Water, Air, Soil Pollut. 2020;231(4).
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- Arif M, Alagawany M, Abd El-Hack ME, Saeed M, Arain MA, Elnesr SS. Humic acid as a feed additive in poultry diets: a review. Iranian journal of veterinary research. 2019;20(3):167-172.
- Taklimi S, Ghahri H, Isakan M. Influence of different levels of humic acid and esterified glucomannan on growth performance and intestinal morphology of broiler chickens. Agricultural Sciences. 2012;03:663-668
- Mudroňová D, Karaffová V, Pešulová T, et al. The effect of humic substances on gut microbiota and immune response of broilers. Food Agric Immunol. 2020;31(1):137-149
Warnings
Always be sure to speak with your healthcare provider before starting any new nutritional supplement when pregnant or nursing. For children, we recommend speaking with your child's pediatrician regarding proper dosing. Store away from children.
If loose stools occur, stop use and notify your healthcare practitioner.
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