Pure Cal/Mag

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Pure Cal/Mag contains 300 mg of calcium as Di-calcium malate and 150 mg of magnesium as Di-magnesium malate per serving (2 capsules). Calcium and magnesium are minerals that work best when taken together due to their synergist relationship. When taken at the same time, the benefits of both minerals are magnified.


Functions of Calcium

  • Bone mineralization
  • Hormone communication (as a second messenger)
  • Calcium functions as an electrolyte
  • Needed for optimal nerve and muscle function

Functions of Magnesium

  • Magnesium has over 700 different functions
  • Regulates hormone production
  • Needed for optimal muscle function
  • Regulates energy production in your body
  • Regulates the nervous system
  • Needed to activate vitamin D
  • Required for optimal methylation

Take 2 capsules per day with a meal, or as directed by your health care professional.


Pure Cal/Mag provides the minerals calcium and magnesium in a 2:1 ratio to ensure a healthy balance of these two essential nutrients—something that can be difficult to achieve solely through diet.

When in balance, calcium and magnesium play vital roles in many areas of human health. Calcium is crucial for muscle contraction, proper blood clotting, wound healing, the secretion of hormones and enzymes, nerve transmission, and for building strong bones and teeth.* Magnesium, one of the most critical minerals in the human body, is involved in over three hundred enzyme reactions and plays a pivotal role in muscle relaxation, energy production, heart health, maintaining proper blood pressure, and supporting healthy blood sugar levels.*

Calcium and magnesium work together in many ways. For instance, calcium is necessary for muscles to contract, while magnesium is needed for muscles to relax. Calcium works to stimulate nerves, while magnesium calms the nerves. Because of these opposing but equally important functions, imbalances in these two nutrients may contribute to suboptimal functioning of multiple systems in the body.

Calcium supplementation has become popular over the last several years for the purpose of supporting bone health. However, bones are more than just calcium, and supplementing calcium without its complementary nutrients— including magnesium—may not have the intended beneficial effect on bone density. (Bone tissue contains 99% of the body’s calcium but also contains as much as 60% of the body’s magnesium.) Overly imbalanced calcium supplementation may actually increase the need for magnesium, a nutrient that is typically already in short supply in the modern diet. (Processing and refining of certain foods, such as whole grains, may reduce their magnesium content. Rich sources of magnesium include beans, nuts and seeds, and select leafy greens.)

Pure Cal/Mag offers calcium and magnesium in a 2:1 ratio: 300 mg calcium and 150 mg magnesium per 2-capsule serving. The body’s requirement for calcium is higher than that for magnesium, but compared to magnesium, calcium is relatively abundant in the food supply, particularly for people whose diets include dairy products. Nevertheless, some individuals may benefit from additional calcium via supplementation and providing magnesium when supplementing with calcium is important because several commonplace factors increase the body’s need for magnesium, including exercise, heavy alcohol or coffee consumption, excessive sweating, and certain commonly used medications. In addition to the roles for magnesium mentioned above, adequate magnesium levels in the body may support restful sleep and help promote physical relaxation as well as mental and emotional calm.


† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


  1. Shen R, Shuai JW. Neuronal modeling with intracellular calcium signaling. Shen Li Xue Bao. 2011 Oct 25;63(5):442-52.
  2. McCarron DA, Morris CD. The calcium deficiency hypothesis of hypertension. Ann Intern Med. 1987 Dec;107(6):919-22.
  3. Weaver CM et al. Calcium plus vitamin D supplementation and risk of fractures: an updated meta-analysis from the National Osteoporosis Foundation. Osteoporosis Int. 2016 Jan;27(1):367-76.
  4. Kirkland AE, Sarlo GL, Holton KF. The role of magnesium in neurological disorders. Nutrients. 2018 Jun 6;10(6):730.
  5. Grober U, Schmidt J, Kisters K. Magnesium in prevention and therapy. Nutrients. 2015 Sep 23;7(9):8199-226.
  6. DiNicolantonio JJ, O’Keefe JH. Magnesium and vitamin D deficiency as a potential cause of immune dysfunction, cytokine storm and disseminated intravascular coagulation in COVID-19 patients. Mo Med. Jan-Feb 2021;118(1):68-73


Always be sure to speak with your healthcare provider before starting any new nutritional supplement when pregnant or nursing. For children, we recommend speaking with your child's pediatrician regarding proper dosing. Store away from children.

If loose stools occur, stop use and notify your healthcare practitioner.


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