† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
- Appel LJ, Moore TJ, Obarzanek E, et al: A clinical trial of the effects of dietary patterns on blood pressure: DASH Collaborative Research Group. NEJM 1997; 336: 1117-1124.
- Taddei S, Virdis A, Ghiadoni L, et al: Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. Circulation 1998; 97: 2222-2229.
- Heller R, Unbehaun A, Schellenberg B, Mayer B, Werner-felmayer G, Werner ER. L-Ascorbic Acid Potentiates Endothelial Nitric Oxide Synthesis via a Chemical Stabilization of Tetrahydrobiopterin. J Biol Chem 2001; 276: 40-47.
- Jaffe R. How to do an ascorbate (vitamin C) calibration (‘C Flush’) to determine personal need. HSC, 2020.
- Dawson EB, Evans DR, Harris WA,Teter MC, McGanity WJ.The effect of ascorbic acid supplementation on the blood lead levels of smokers. JACN. 1999: 18: 166-170.
- Carr AC, Zhu BZ, Frei B.Potential antiatherogenic mechanisms of ascorbate (vitamin C) and alpha-tocopherol (vitamin E). Circ Res 2000; 87(5): 349-54.
- Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci USA. 1993;90(17): 7915-22.
- McCully K. Chemical pathology of homocysteine. III. Cellular function and aging. Ann Clin Lab Sci. 1994; 24(2): 134-52.
- Anderson R, Smit MJ, Joone GK, Van Staden AM. Vitamin C and cellular immune functions. Protection against hypochlorous acid-mediated inactivation of glyceraldehyde-3-phosphate dehydrogenase and ATP generation in human leukocytes as a possible mechanism of ascorbate-mediated immunostimulation. Ann NY Acad Sci. 1990; 587: 34-48.
Always be sure to speak with your healthcare provider before starting any new nutritional supplement when pregnant or nursing. For children, we recommend speaking with your child's pediatrician regarding proper dosing. Store away from children.